package aduAnes

// These are general constants for common constant anesthetics in mg/kg or mcg/kg.
// Constants are in mg/kg unless specified

const (
	//Pre-Medication
	//Dart medications are from the Journal of OMFS 1995, Intramuscular ketamine, midazolam, and glycopyrrolate for pediatric sedation
	GlycoDart = 0.005
	KetDart   = 3
	MidDart   = 0.05
	MidPO     = 0.6
	// The optimal succinylcholine dose for intubating emergency patients: retrospective comparative study Journal of Anesthesia 2009
	MidwKet = 0.25
	KetPO   = 3

	//Induction

	// Propofol induction dose based on journal: Anesthesiology, 1989 Aug;71(2):260-77. Propofol: a new intravenous anesthetic.
	PropInduct = 2
	// Etomidate induction dose based on averaging induction doses from journal: BJA: Volume 91, Issue 3, September 2003, Pages 341–346
	EtomInduct = 0.25
	// Rocuronium: Doses based on Anesthesia Residency training at Loma Linda University Medical Center
	Roc = 0.6
	// Ketamine induction dose based on CLINICAL STUDIES OF INDUCTION AGENTS XXXVI: KETAMINE BJA 1970
	KetInduct = 2
	// Only 40 mg are needed to prevent pain on induction with propofol:
	// Anethesia & Analgesia, March 1996, Prevention of Pain on Injection of Propofol: A Comparison of Lidocaine with Alfentanil
	// Lidocain for the reduction of MAC has poor studies. Most are from Vetanary Anesthesia experiments in dogs, cat, & hourses
	// The constant 1 mg/kg is taken from my time in residency training at Loma Linda University
	// Basically at this time, Jan 2020, evidence for Lidocaine administration for induction is limited to animal studies.
	Lido = 1
	// ED95 = 0.3 mg/kg
	// Choice of 0.45 taken from Libyan Journal of Medicine "The optimal succinylcholine dose for intubating emergency patients:
	// retrospective comparative study" 2011
	SuccRapSeq = 0.45

	//Pain Medications

	Fent    = 0.0015
	HyMorph = 0.005
	//Infusion rate coefficient describing the dose required to achieve a OAA/S level of 2 in 50% of the patients (ED50): 0.043 μg · kg. Remifentanil as an Analgesic Adjunct in Local/Regional Anesthesia and in Monitored Anesthesia Care Anesthesia & Analgesia 1999.
	Remi   = 0.043 //micro-grams / kg
	Ketor  = 0.5
	Dexmed = 0.35

	//Emergency Drugs

	//SuccRapSeq = 0.45
	LarSpzSucc = 0.1
	EmergAtro  = 0.02
	EmergEpi   = 0.01
	Amiodar    = 5
	Adenos     = 0.1

	//Inhalational Agents

	NitroMAC = 105
	HaloMAC  = 0.751
	IsoMAC   = 1.14
	SevoMAC  = 1.98
	DesMAC   = 5.93

	//Nausea Emesis

	// Anesthesia 1994 Single dose Zofran for prevention of PONV; PMID: 8129156
	Ondan   = 0.1
	Metoc   = 0.1
	Aprepit = 3
	Bena    = 0.25
	Dex     = 0.2

	//Emergance Drugs

	Suggam = 4
	Neo    = 0.05
	Glyco  = 0.01
	Narcan = 0.01
)